Virulent bacterial infection improves aversive learning performance in Drosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Virulent bacterial infection improves aversive learning performance in Drosophila melanogaster.
Virulent infections are expected to impair learning ability, either as a direct consequence of stressed physiological state or as an adaptive response that minimizes diversion of energy from immune defense. This prediction has been well supported for mammals and bees. Here, we report an opposite result in Drosophila melanogaster. Using an odor-mechanical shock conditioning paradigm, we found th...
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Melioidosis is a serious infectious disease endemic to Southeast Asia and Northern Australia. This disease is caused by the Gram-negative bacterium Burkholderia pseudomallei; Burkholderia thailandensis is a closely-related organism known to be avirulent in humans. B. thailandensis has not previously been used to infect Drosophila melanogaster. We examined the effect of B. thailandensis infectio...
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The fruit fly Drosophila melanogaster is one of the premier model organisms for studying the function and evolution of immune defense. Many aspects of innate immunity are conserved between insects and mammals, and since Drosophila can readily be genetically and experimentally manipulated, they are powerful for studying immune system function and the physiological consequences of disease. The pr...
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Many pathogens engage host cell surface glycosaminoglycans, but redundancy in pathogen adhesins and host glycosaminoglycan-anchoring proteins (heparan sulfate proteoglycans) has limited the understanding of the importance of glycosaminoglycan binding during infection. The alpha C protein of group B streptococcus, a virulence determinant for this neonatal human pathogen, binds to host glycosamin...
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Learning can be defined as a behavioral change linked to previous individual experience. Animal models are useful in the study of learning, and the fruit fly Drosophila melanogaster has been used for 30 years to this end (see Le Bourg & Buecher, 2002, for a review). Establishing paradigms for the study of learning is not an easy task and requires, in addition to replicability, accurate control ...
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ژورنال
عنوان ژورنال: Brain, Behavior, and Immunity
سال: 2014
ISSN: 0889-1591
DOI: 10.1016/j.bbi.2014.05.008